Short Video Clip Library
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Name Seminar Title Description Category
Alejandro Sánchez-Alvarado Alejandro Sánchez-Alvarado Regeneration experiments from the 1700s
(10:28 Min.)
Early experiments in regeneration and the implication for philosophy and religion at the time are described. Developmental Biology and Evolution
Alejandro Sánchez-Alvarado Alejandro Sánchez-Alvarado Animal regeneration
(01:25 Min.)
Regeneration throughout the animal kingdom. Developmental Biology and Evolution
Alejandro Sánchez-Alvarado Alejandro Sánchez-Alvarado Regeneration in Planaria
(02:38 Min.)
Planaria flat worms demonstrate an amazing regenerative ability after dissection. Developmental Biology and Evolution
Alejandro Sánchez-Alvarado Alejandro Sánchez-Alvarado More plasticity in Planaria
(02:17 Min.)
Under conditions of starvation, planaria shrink while maintaining perfect body proportions. Developmental Biology and Evolution
Alejandro Sánchez-Alvarado Alejandro Sánchez-Alvarado The major organ systems of Planaria
(06:15 Min.)
The major organ systems of Planaria are described, followed by a fluorescent microscopy movie visualizing the organ systems along the dorsal ventral axis. Developmental Biology and Evolution
Randy Schekman Randy Schekman Synaptic vesicle fusion in nerve cells
(05:25 Min.)
A series of electron micrographs (both thin section and freeze fracture) of a nerve cell showing the docking and fusion of synaptic vesicles with the plasma membrane. Biological Mechanisms
Randy Schekman Randy Schekman Secretory vesicle fusion in yeast
(06:06 Min.)
Electron micrographs of budding yeast cell showing secretory vesicles fusing with the plasma membrane in a manner similar to that seen in nerve cells. Biological Mechanisms
Randy Schekman Randy Schekman The COPII protein coat
(02:02 Min.)
Electon micrographs of COPII vesicles formed in an in vitro budding assay showing the regular array of proteins on the vesicle surface. Biological Mechanisms
Randy Schekman Randy Schekman Vesicle budding and targeting
(04:38 Min.)
An animation of COPII coated vesicles budding from the endoplasmic reticulum and trafficking to the Golgi. Biological Mechanisms
Lucy Shapiro Lucy Shapiro Antibiotic resistance and how it develops
(05:36)
Antibiotic resistance and how it develops. Global Health and Energy
Lucy Shapiro Lucy Shapiro Where did pathogenic E. coli 0157:H7 come from?
(02:48 Min.)
“Natural” genetic engineering between harmless E.coli and pathogenic Shigella bacteria produced pathogenic E. coli 0157. Global Health and Energy
Julie Theriot Julie Theriot Actin based cell motility
(05:06 Min.)
Examples of moving neutrophils, amoeba and fish keratinocytes or skin cells. Biological Mechanisms
Julie Theriot Julie Theriot Force production by actin
(00:59 Min.)
Models for how polymerization of actin filaments can produce enough force to push forward the leading edge of a cell at the speeds seen in living cells. Biological Mechanisms
Julie Theriot Julie Theriot Listeria as a model system
An epithelial cell infected with Listeria monocytogenes. Listeria are moving around the cell with obvious “comet tails” of actin. Biological Mechanisms
Julie Theriot Julie Theriot Speed of listeria movement
(02:04 Min.)
Comparison of the relative speed of listeria moving through cytoplasm with that of a nuclear submarine moving through the ocean. Biological Mechanisms
Julie Theriot Julie Theriot In vitro actin comet tail reconstitution
(04:14 Min.)
Polystyrene beads coated with bacterial ActA protein act much like listeria and can move through cytoplasmic extracts with actin “comet tails”. Biological Mechanisms
Julie Theriot Julie Theriot History dependent effects in cell movement?
(1:39 Min.)
Actin rearrangement in motile cells may be dependent upon the recent history of the cell. Biological Mechanisms
Julie Theriot Julie Theriot Morphological Diversity
(02:02 Min.)
Morphological diversity in eukaryotic, single-celled organisms. Biological Mechanisms
Ron Vale Ron Vale Intracellular motility
(03:15 Min.)
Organelle movement and cell division are visualized by video microscopy. An animation of microtubules, molecular motors and vesicle movement depicts activity inside of a mammalian cell. Biological Mechanisms
Ron Vale Ron Vale The kinesin motor
(01:09 Min.)
Description of kinesin structure and a cartoon diagram of the molecule. Biological Mechanisms
Ron Vale Ron Vale Structural rearrangements in motor proteins
(03:36 Min.)
Animation of changes in the protein structure of kinesin and myosin, as a result of the hydrolysis of ATP. Biological Mechanisms
Ron Vale Ron Vale In vitro motility assays
(02:33 Min.)
Kinesin movement along microtubules. Biological Mechanisms
Ron Vale Ron Vale Animation of a beating heart
(02:12 Min.)
Sarcomeres contract and muscle myosin moves along actin filaments. Biological Mechanisms
Ron Vale Ron Vale TIRF microscopy
(01:02 Min.)
Single molecule total internal reflection fluorescent (TIRF) microscope setup and explanation with live video single molecule movement. Biological Mechanisms
Ron Vale Ron Vale Optical trap microscope
(01:36 Min.)
Microscope setup and explanation with live video of a dynein molecule captured in the trap. Biological Mechanisms
Ron Vale Ron Vale Spindle formation
(01:00 Min.)
Image of a metaphase spindle and video of first steps in spindle formation. Biological Mechanisms
Ron Vale Ron Vale How are spindle microtubules made?
(05:35 Min.)
Part 3 #2 Are they nucleated from centrosomes, chromosomes or independently of either of these structures? Biological Mechanisms
Xiaodong Wang Xiaodong Wang Apoptosis during development
(00:59 Min.)
Apoptosis during development. Cell Biology & Medicine
Xiaodong Wang Xiaodong Wang Morphological and biochemical markers of apoptosis
(06:05 Min.)
Examples of cell blebbing, chromatin chondensation, phosphatidylserine flipping in the plasma membrane, caspase activation and DNA fragmentation as markers of apoptosis. Cell Biology & Medicine
Xiaodong Wang Xiaodong Wang Caspase activation
(01:35 Min.)
Proteolytic activation of caspases 3 and 7. Cell Biology & Medicine
Xiaodong Wang Xiaodong Wang The mitochondrial or intrinsic apoptotic pathway
(04:01 Min.)
Summary of the steps involved in forming the apoptosome and activating caspases 3 and 7 resulting in cell death. Cell Biology & Medicine
Eric Wieschaus Eric Wieschaus Early Drosophila embryo development
(06:11 Min.)
The events leading from a single celled embryo to an embryo with many cells with distinct functions are described. Developmental Biology and Evolution
Eric Wieschaus Eric Wieschaus A movie of embryo development
(01:32 Min.)
The movement of cells and the formation of folds in a GFP labeled Drosophila blastoderm stage embryo are seen in this movie. Developmental Biology and Evolution
Eric Wieschaus Eric Wieschaus Regulation of gene expression
(02:20 Min.)
Spatial and temporal gene expression at the blastoderm stage are regulated by Bicoid protein. Developmental Biology and Evolution
Eric Wieschaus Eric Wieschaus Bicoid protein gradient in the embryo
(03:26 Min.)
Bicoid protein gradient in the embryo. Developmental Biology and Evolution
Eric Wieschaus Eric Wieschaus Movie of the Bicoid protein gradient
(02:26 Min.)
This movie shows the establishment of an EGFP labeled Bicoid gradient in the Drosophila embryo. Developmental Biology and Evolution
Eric Wieschaus Eric Wieschaus How the Bicoid gradient may be formed
(02:29 Min.)
An embryo with GFP labeled histone allows movement of the nuclei and cytoplasm during nuclear replication to be visualized. Wieschaus discusses how a Bicoid gradient may be established not by diffusion but by random flow of the cytoplasm. Developmental Biology and Evolution
Eric Wieschaus Eric Wieschaus The role of Bicoid in all fly species
(03:75 Min.)
Development is regulated by a Bicoid gradient in all Diptera (fly) species. Developmental Biology and Evolution
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